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order STA4783 Aside from this report only two other studies
2019-06-05
Aside from this report, only two other studies of dexrazoxane use in adult AML patients have been published. In a series of seven patients with AML, Lemez and Maresova reported that the administration of dexrazoxane 30min before daunorubicin (dose 8-13x higher than daunorubicin) or mitoxantrone (dos
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br Methods br Results Globally CCI increased by
2019-06-05
Methods Results Globally, CCI increased by 0·82 percent points a year, from 54·8% in 1994, to 71·2% in 2014 (CCI estimates at national level, stratified by wealth quintiles and place of residence, are presented in the appendix, pp 6–15). This gain was largely driven by low-income countries, wh
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Although no GWAS results have been reported so far from
2019-06-05
Although no GWAS results have been reported so far from Asian populations, the candidate gene approach identified SNPs in 4q25 and 1q21 as being associated with AF in Asian populations [19,20]. Conflicting data are reported in terms of 16q22; it is associated with AF in Chinese Han [37], but not in
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Introduction Classically increased cardiac fibrosis has been
2019-06-05
Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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This patient had sick sinus
2019-06-05
This patient had sick-sinus syndrome and also took sotalol for the prevention of VT related to ARVC. Therefore, constant atrial pacing was indispensable for maintaining a physiological atrial rhythm. Frequent right ventricular pacing is known to cause left ventricular dysfunction, myocardial perfusi
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Staurosporine For the pocket a cm incision was made along th
2019-06-05
For the pocket, a 6cm incision was made along the predefined Langer’s lines. Subcutaneous dissection was carried out using an electrosurgical cutting and coagulation device, parallel to the incision, down to the fascia overlying the latissimus dorsi muscle (shining transparent membrane). Intermuscu
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Of note cases reported by
2019-06-01
Of note, cases reported by Britton et al. and Keung et al. rely on the demonstration of CD7 and TDT along with myeloid markers to classify the blasts as “biphenotypic” [8,9]. Expression of CD3 is not reported by the authors and these cases would not meet the current 2008 WHO criteria for MPAL. Age
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Perhaps the greatest challenge however
2019-06-01
Perhaps the greatest challenge however, relates to the epidemiology of this disease and understanding the interactions that occur between the reservoir hosts (ie, monkeys), vectors, and human activities that enable transmission. Understanding these complex behavioral and ecological interactions will
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br As one of the
2019-06-01
As one of the few countries that have achieved Millennium Development Goals 4 and 5, China has had a remarkable decline in under-5 mortality rate in past three decades. Drivers of such rapid improvement in China have been widely discussed. In , Chunhua He and colleagues report a decline in under-
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Chronic hepatitis B virus HBV infection is prevalent in
2019-06-01
Chronic glycoprotein inhibitors virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV contin
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Phosphorus is essential for organic activity such as cellula
2019-06-01
Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and ddhCTP exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such as adenosine triphosphat
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At least genes are associated with familial LQTS
2019-06-01
At least 15 genes are associated with familial LQTS, with 3 of these genes accounting for 70–75% of cases [5]. Despite advances in the understanding of the molecular basis of LQTS, challenges remain in making the clinical diagnosis. Importantly, between 10–40% of gene carriers have normal QT interva
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En las reflexiones sobre la Isla del
2019-06-01
En las reflexiones sobre la “Isla del Encanto” de María Teresa Cortés en su aportación titulada “La configuración de la nación en la narrativa histórica puertorriqueña y el sistema de prácticas ecológicas, siglo ” retoma la labor informativa sobre Puerto Rico, hecha por el funcionario español de ori
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La reivindicaci n del m rtir revolucionario El proceso
2019-06-01
La reivindicación del mártir revolucionario El proceso del egp dio lugar urat1 inhibitor consolidar un frente de estudiantes constituido con su línea política, trabajo continuo del estudiantado identificado con ello; respecto a la dirección de esta organización, carecemos de comunicados o publicaci
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GDC-0994 In conclusion we demonstrated that cells with
2019-06-01
In conclusion, we demonstrated that GDC-0994 with the standard Ph had no detectable BCR–ABL1 KD mutations and that they were responsive to imatinib therapy, while cells with the variant translocation harbored two KD mutations, a previously described one and a never previously reported one [5]. Thes
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