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Many of the emerging non vaccine serotypes
2019-05-21
Many of the emerging non-vaccine serotypes in carriage after PCV13 implementation (11A, 15B/C, 15A, 21, 23B, and 35F) show low potential for causing invasive disease, but some—eg, 12F, 22F, 24F, 8, and 9N—have high disease potential. Moreover, in vulnerable populations (eg, immunocompromised people)
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On what might an argument for a fairer distribution of
2019-05-21
On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater
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br Epidemiology Electrophysiological BrS phenotypes occur pr
2019-05-21
Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults (by latrunculin a rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. However, the Br
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In several Western reports from large scale comparative
2019-05-21
In several Western reports from large-scale comparative studies and epidemiological surveys, there was no significant difference in the incidence of thromboembolism between paroxysmal and persistent AF patients [46,47]. Data from our institution suggested that the incidence of cardiogenic thromboemb
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pka inhibitor One week after the CCRT she was brought to our
2019-05-21
One week after the CCRT, she was brought to our emergency department due to fever, severe general weakness, and severe oral pain. Her Sicca syndrome-related xerostomia had worsened due to radiotherapy and was complicated with severe stomatitis, which made oral intake difficult. She took traditional
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urokinase The importance of the microenvironment for
2019-05-21
The importance of the microenvironment for cancer development and progression is now widely recognised, but it is worth reminding ourselves that this is a relatively young area of research. Anyone searching PubMed today using the terms “” will find over 22,000 scientific publications, with around 30
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The data obtained in our work showed that AMD was
2019-05-21
The data obtained in our work showed that AMD was able to inhibit complex I activity and ATP biosynthesis in MRC-5 cells. These effects were accompanied by an increase in lipid and protein oxidative damage and a decrease in NO levels and superoxide dismutase and catalase activities, suggesting that
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The presence of the anthelmintic levamisole is
2019-05-21
The presence of the anthelmintic levamisole is also worrying because it has been withdrawn from many markets for human use owing to its association with agranulocytosis. The recent epidemic of necrotising vasculitis resulting from “cutting” cocaine with levamisole suggests links between criminals wh
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With the availability of vaccines screen and treat approache
2019-05-21
With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement. The expanding focus from basic research, drug development, and clinical trials th
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Although preoperative rehabilitation may have
2019-05-20
Although preoperative rehabilitation may have a strong impact on survival if additional patients are qualified for curative resection, yet strong evidence remains lacking to support the regimens for patients who have lung cancer. This may be due to, in part, the relatively brief pppa manufacturer of
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AC regimens have also demonstrated
2019-05-20
AC regimens have also demonstrated better preventive effects in terms of stroke than AP regimens [18–20], whereas major or minor bleeding events in Japanese patients with cardiovascular diseases were reported to be more frequent in patients taking AC than in those taking AP regimens [21]. To underst
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Even with the limitations in the available
2019-05-20
Even with the limitations in the available data on DALYs, the funding gap is huge. The Research Investments in Global Health study analysed public and philanthropic infectious disease research awards to UK institutions (1997–2013), and compared them to the burden in DALYs, describing a new metric of
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De hecho la desordenada colecci n de los datos etnogr
2019-05-20
De hecho, la desordenada colección de los datos etnográficos se encuentra varias veces en conflicto con la propuesta de un proyecto sistemático que el fraile busca plantear, sin éxito, en el exordio de su obra. En las primeras páginas de la Relación, Pané esboza los confines de un modelo hermenéutic
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O ensaio de Volodia Teitelboim
2019-05-20
O ensaio de Volodia Teitelboim enfatizou os discursos de Fidel Castro desde quando seu grupo assumiu o poder em Cuba, logo após MC1568 vitória em Sierra Maestra. Sua habilidade com as palavras foi destacada por Teitelboim, bem como seu caráter de coragem e retidão. Tais qualidades do líder revolucio
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Paralelamente Chucho Hegel increpa al Profesor Sin dejar de
2019-05-20
Paralelamente, Chucho Hegel increpa al Profesor: “Sin dejar de ser el mismo, te has convertido en el otro como el blanco que se pinta de negro en el teatro bufo”. Pone, así, sobre el tapete, el que quizá sea el mayor de los demonios contra los que lucha el Profesor, personaje, éste, que deja espacio
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