• Effective medical management of cutaneous metastasis arising

  2019-04-26

  

  Effective medical management of cutaneous myosin arising from internal malignancy is usually difficult. Systemic chemotherapy and local excision or radiation therapy may be considered. As for metastatic ampulla of Vater cancer, the more recent histological differentiation in intestinal and pancreat

• Since many decades bone tumours have stimulated imagination

  2019-04-26

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• protoporphyrin ix br A tactical change in research and advoc

  2019-04-25

  

  A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di

• The study by Mijiti and

  2019-04-25

  

  The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai

• Introduction The hippocampus is a critical brain

  2019-04-25

  

  Introduction The hippocampus is a critical brain region for episodic memory formation in rodents and humans [1]. Hippocampal neurons, especially CA1 neurons, are highly vulnerable to ischemic injury [2], and failure of hippocampal function causes memory impairment and reduced cognitive ability [3,4

• br Algorithm of treatment approach in Brugada syndrome

  2019-04-25

  

  Algorithm of treatment approach in Brugada syndrome patients with electrical storm Fig. 4 shows the flow diagram of how we treat BrS patients with ES. Patients are admitted to the ICU and should be well sedated, and some may require general anesthesia with endotracheal intubation. The patients ar

• Cell adhesion to extracellular matrix requires

  2019-04-25

  

  Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp

• br Introduction Magnetic resonance imaging MRI

  2019-04-25

  

  Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) biotin-LC-LC-tyramide sometimes does not allow diff

• retinoid x receptor br Materials and methods br

  2019-04-25

  

  Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of

• ddr1 El poema arranca de una contemplaci n del paisaje

  2019-04-25

  

  El poema arranca de una contemplación del paisaje en pleno mes de noviembre. El “verdor” de las siemprevivas contrasta con un panorama vegetal dominado por la “grisura” de la deshojadura otoñal. La mirada del yo poético se fija preferentemente “en las siemprevivas y en las plantas perennes”. Esta pe

• Pero en los a os noventa como refere

  2019-04-25

  

  Pero en los años noventa, como refere Brito, al inventariarse los resultados de la estrategia de desarrollo y de las reformas adelantadas en la década anterior, es decir ante una revisión “crítica” del “Consenso de Washington”, fue evidente que los costos en términos de inequidad y dualización soci

• Introduction This document does not address the indications

  2019-04-24

  

  Introduction This document does not address the indications of genetic testing in patients affected by inherited arrhythmias and their family members. Diagnostic, prognostic, and therapeutic implications of the results of genetic testing also are not included in this document because this topic has

• The clinical spectrum of intracranial

  2019-04-24

  

  The clinical spectrum of intracranial hemorrhage is similar for patients treated with warfarin and dabigatran [10]. Absolute rates of intracranial hemorrhage across all sites and of both fatal and traumatic intracranial hemorrhages are lower with dabigatran than with warfarin [10]. Concomitant aspir

• br Conflict of interest br Introduction

  2019-04-24

  

  Conflict of interest Introduction Gastric cancer is a major cause of cancer deaths worldwide, particularly in East Asia. Metastatic gastric cancer is associated with poor outcomes. The median overall survival of metastatic gastric cancer ranges from 9 to 13 months despite treated with systemic

• br Results br Discussion br Conclusions br

  2019-04-24

  

  Results Discussion Conclusions Disclosures Conflict of interest Financial support Introduction Stroke is one of the top five common causes of mortality in Malaysia with a rate at 8.43/100,000 hedgehog inhibitor [1,2]. Stroke impact is not limited to physical disabilities that s

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