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After maintenance activities the component state is not the
2018-11-15
After maintenance activities, the component state is not the exact combination of as good as new and as bad as old, and it may be somewhere between two extreme states, i.e., the so-called imperfect maintenance. An imperfect maintenance model was built ingeniously to reveal the relationship among mai
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Other important issues have also
2018-11-15
Other important issues have also been motivated by this paper as to pursue qualitative research. On one hand, Meglio and Risberg (2010) suggest that “instead posit that the M&A field has become marred by a set of bureaucratic method techniques that trivialize research with little organizational rele
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br Conclusions and practical implications Since the
2018-11-15
Conclusions and practical implications Since the results of this study showed that artificial neural networks have an impressive ability in analyzing customer satisfaction, perceived value, and loyalty, it is recommended that companies use this state of the art data analytics technique in order t
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The gold standard of identification by bacterial culture has
2018-11-15
The gold standard of identification by bacterial culture has been unable to meet the demand of bacterial biotin-LC-LC-tyramide analysis, because >90% of the clinical bacteria cannot be cultured. Next-generation sequencing (NGS) provides a new technology to study the microbiota and pathogenic mechan
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domoic acid Space syntax research aims to develop strategies
2018-11-14
Space syntax research aims to develop strategies for describing the configurations of occupied/inhabited spaces to articulate underlying social meanings. This process enables the development of secondary theories or practical explanations on the effects of spatial configuration on various social or
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smad pathway where is some parameter eigenvalue A B C
2018-11-14
where β is some parameter (eigenvalue); A, B, C and D are the unknown coefficients. The general solution of the problem is expressed by the sum The coefficients A, B, C and D in formula (16) are determined from the boundary conditions at the longitudinal edges: y=0 and y=1. Satisfying the condi
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Grau looks beyond this and affirms that Spanish universities
2018-11-14
Grau (2012) looks beyond this and affirms that Spanish universities are not within the actual political priorities of policy makers, and that one of the purposes of the European Commission is for Spanish universities to implement tools of strategic management to become more competitive and responsib
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glucose transporter Second the uncertainty in the vector and
2018-11-14
Second, the uncertainty in the vector and human parameters affect the value of DEP through VC and the threshold value for intensity. All six vector parameters depend on temperature. The female vector-to-human population ratio depends on temperature the same way as longevity (Brady et al., 2014). The
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However one might question whether effective compounds that
2018-11-14
However, one might question whether effective compounds that do not bind to the C-terminal domain of PrP or that have other molecular targets besides PrP () will be excluded from this virtual screening. In the first case, docking with at least the 90–231 domain of the prion protein will prove useful
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miR mimics are also currently under Phase I clinical
2018-11-14
miR-16 mimics are also currently under Phase I clinical trials for patients with Malignant Pleural Mesothelioma (MPM) and Advanced Non-Small Cell Lung Cancer (NSCLC) that have failed standard therapy. These miR-16 mimics were delivered intravenously, using EnGeneIC Delivery Vehicle (EDV)-Packaging,
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The human PD mutant A L exhibiting increased affinity for
2018-11-14
The human PD-1 mutant (A132L) exhibiting increased affinity for both PD-L1 (45-fold) and PD-L2 (30-fold) was selected for further studies and the generation of a soluble chimeric Ig fusion protein (HA PD-1 Ig). As expected, compared to wild type PD-1 Ig, the HA PD-1 Ig showed significantly enhanced
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It has been known for some
2018-11-14
It has been known for some 30years now that manifest autoimmune disease is correlated with changes in the glycosylation of antibodies (), and the list of autoimmune diseases with alteration in IgG glycosylation is rapidly growing with increasingly detailed analysis of glycoforms (for a review see ()
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Interestingly we found that high salt also increased
2018-11-14
Interestingly, we found that high salt also increased the translocation of p65 as well the degradation of IκB in RAW 264.7 macrophages (Supplementary Fig. 5), which is in parallel with a previous report (Roth et al., 2010). These data indicates that the NF-κB pathway is activated by hypertonicity in
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The most surprising data for us was the behavior
2018-11-14
The most surprising data for us was the behavior of α-synuclein protein; it accumulated in the dopaminergic neurons of the substantia nigra in response to MPTP treatment, and it failed to accumulate during the treatment with KUSs and esculetin (Fig. 9). Related with this, very recently it has been r
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Fig demonstrates cell damage induced by ultra sonication and
2018-11-14
Fig. 2 demonstrates cell damage induced by ultra-sonication and evaluated by estimation of the total protein content of the cell suspensions. The data demonstrates that ultra-sonication of Rosiglitazone manufacturer induces varying degrees of cell damage directly proportional to the duration of ultr
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