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Effective medical management of cutaneous metastasis arising
2019-04-26
Effective medical management of cutaneous histone acetyltransferase arising from internal malignancy is usually difficult. Systemic chemotherapy and local excision or radiation therapy may be considered. As for metastatic ampulla of Vater cancer, the more recent histological differentiation in intes
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Initial radiographs demonstrated an aggressive lesion in the
2019-04-26
Initial radiographs demonstrated an aggressive lesion in the medial condyle of the distal right femur (Figs. 1A and B). CT obtained to characterize matrix showed an aggressive lesion with a focus of dense linear matrix (Fig. 2) with intervening lucent areas. The lesion was felt to be indeterminate a
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Preamble The J wave syndromes
2019-04-26
Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology hiv integrase inhibitor over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugad
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All photographs colour or black and white should be
2019-04-26
All photographs—colour or black and white—should be , along with the required text and any supporting material for online publication. Please select Photograph as the article type. If a digital camera is used please set it to the highest possible quality setting and submit images as JPEG files. If y
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Genomic DNA was isolated from blood after
2019-04-26
Genomic DNA was isolated from blood after obtaining written informed consent. Genetic screening for LQT-1 (KCNQ1), -2 (KCNH2), -3 (SCN5A), -5 (KCNE1), -6 (KCNE2), -7 (KCNJ2), -9 (CAV3), -10 (SCN4B), and -12 (SNTA1) was performed by PCR and direct DNA sequencing. No order monensin was found in these
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Effective medical management of cutaneous metastasis arising
2019-04-26
Effective medical management of cutaneous myosin arising from internal malignancy is usually difficult. Systemic chemotherapy and local excision or radiation therapy may be considered. As for metastatic ampulla of Vater cancer, the more recent histological differentiation in intestinal and pancreat
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Since many decades bone tumours have stimulated imagination
2019-04-26
Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh
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protoporphyrin ix br A tactical change in research and advoc
2019-04-25
A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di
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The study by Mijiti and
2019-04-25
The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai
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Introduction The hippocampus is a critical brain
2019-04-25
Introduction The hippocampus is a critical brain region for episodic memory formation in rodents and humans [1]. Hippocampal neurons, especially CA1 neurons, are highly vulnerable to ischemic injury [2], and failure of hippocampal function causes memory impairment and reduced cognitive ability [3,4
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br Algorithm of treatment approach in Brugada syndrome
2019-04-25
Algorithm of treatment approach in Brugada syndrome patients with electrical storm Fig. 4 shows the flow diagram of how we treat BrS patients with ES. Patients are admitted to the ICU and should be well sedated, and some may require general anesthesia with endotracheal intubation. The patients ar
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Cell adhesion to extracellular matrix requires
2019-04-25
Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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br Introduction Magnetic resonance imaging MRI
2019-04-25
Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) biotin-LC-LC-tyramide sometimes does not allow diff
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retinoid x receptor br Materials and methods br
2019-04-25
Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of
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ddr1 El poema arranca de una contemplaci n del paisaje
2019-04-25
El poema arranca de una contemplación del paisaje en pleno mes de noviembre. El “verdor” de las siemprevivas contrasta con un panorama vegetal dominado por la “grisura” de la deshojadura otoñal. La mirada del yo poético se fija preferentemente “en las siemprevivas y en las plantas perennes”. Esta pe
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