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br Data considerations and methodology
2018-11-07
Data considerations and methodology We assembled yearly counts of suicides that occurred from the fall of the monarchy in 1910–2013. During this period, Portuguese population increased from less than 6 million to more than 10.5 million. To take this fact into consideration, we computed suicides p
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Specifically with regard to the role of the exchange
2018-11-07
Specifically, with regard to the role of the exchange rate policy, on the one hand, the level of the exchange rate is a key price for developing countries, therefore, when defining the profitability of production by the ratio of prices between tradable and non-tradable goods, the exchange rate direc
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The proteasome activator gamma encodes the
2018-11-07
The proteasome activator 28 gamma () encodes the gamma subunit of the 11S regulator of the immunoproteasome, a modified proteasome that processes class I MHC peptides. PA28γ is a multifunctional protein, implicated in the degradation of important LDC000067 cost regulatory proteins in an ATP-indepen
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We found evidence of similar
2018-11-07
We found evidence of similar alterations in levels of certain natural autoantibodies (low IgM anti-PC and high IgG anti-MDA) among patients with RHD, although the effect size was smaller than for HIV infection. As an autoimmune condition, RHD may be associated with global immune dysregulation that a
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br Conclusion br Disclosure The authors declare
2018-11-07
Conclusion Disclosure The authors declare no conflicts of interest. I.R. is supported by the Wellcome Trust [103952/Z/14/Z]. Hepatocellular carcinoma (HCC) is a type of liver cancer, causing the highest mortality in the world (). Although surgical operation or other intervention therapies a
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Participant baseline characteristics and outcome measures ar
2018-11-07
Participant baseline characteristics and outcome measures are summarized in Tables 1 and 2. The mean FPG, 1h, and 2h plasma prostaglandin receptors levels were 4.3mmol/l, 7.7mmol/l, and 6.6mmol/l, respectively. Using the IADPSG criteria, there were 1779 (N=12,889, 13.8%) women diagnosed with GDM who
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Regarding the change of blood Pls levels after
2018-11-07
Regarding the change of blood Pls levels after treatment, there were significant differences between the treatment and placebo groups in mild AD patients. Plasma PlsPE in the placebo group decreased significantly after treatment, whereas that of the treatment group remained unchanged. Some studies s
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br Materials and Methods br Results br
2018-11-07
Materials and Methods Results Discussion We previously demonstrated the importance of the WNK4–OSR1/SPAK–NCC signaling cascade in the kidney for blood pressure regulation (Uchida, 2014). However, the extrarenal roles of WNK4 still required clarification. In this study, we found that WNK4 re
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The CRUSADE Can Rapid Risk Stratification of Unstable Angina
2018-11-07
The CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines) bleeding score has been recently introduced to predict bleeding in non-STEMI patients (Subherwal et al., 2009). A patient\'s CRUSADE Bleeding Score eq
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The complexity of identifying gene environment
2018-11-07
The complexity of identifying gene-environment interactions for Crohn\'s disease should be acknowledged. It is important to understand the design of the studies and the methodical implications of grouping multiple genetic variants into a single analysis. Helbig et al. were the first to use a case-on
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br Tasas de inter s artificialmente bajas
2018-11-07
Tasas de interés “artificialmente bajas” Este fenómeno es lo que a sospecha de muchos (, Economist; 2016) ha provocado que el mundo viva con una inusual y extravagante liquidez global entre los mercados financieros de manera artificial. Como se aprecia en la gráfica 1, tanto las expectativas de
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Cell Cycle Compound Library br Phosphorylated proteins were
2018-11-07
Phosphorylated proteins were enriched from the total protein extract using the Al(OH)3-MOAC method as previously described with modifications [6]. Approximately 8mg of total protein extract was added to 2g of Al(OH)3. After centrifugation (6000g for 10min), the matrix with retained proteins was wa
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Data experimental design materials and methods br Acknowledg
2018-11-07
Data, experimental design, materials and methods Acknowledgments This research was supported by funding from JSPS KAKENHI (22580136, 24658228 and 26712023); and Kyushu University Interdisciplinary Programs in Education and Projects in Research Development (P&P A-type, 25005). Data, experiment
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Based on these findings we
2018-11-07
Based on these findings we have proposed a working model that Dsg3 competes with inactive Src for binding to the scaffolding domain of caveolin-1, and thus causes Src to release from binding to caveolin-1, that leading to its auto-activation (Fig. 5B). This working model opens up a new avenue for fu
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The discount rates and factors
2018-11-07
The discount rates and factors reported in this paper are derived based on an estimation of the Cox-Ingersoll-Ross (CIR) stochastic interest rate model [1]. The data can then be used to evaluate investment projects, even when their cash flows occur in the distant future. In the CIR model, the dynam
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