• br Results br Discussion In this

  2018-11-02

  

  Results Discussion In this study we provide evidence that the N-terminal end of CXCL12, a region containing CXCR4 binding and activation domains, is sufficient to induce both migration and proliferation of SVZ-born neuroblasts. Our experimental approach was to synthesize peptides that are anal

• Here we used iPSCs to generate cardiomyocytes by reprogrammi

  2018-11-02

  

  Here, we used iPSCs to generate cardiomyocytes by reprogramming skin fibroblasts from two patients carrying dissimilar LQTS mutations. Associated with LQT2, HERG-A422T produces trafficking-defective HERG K+ mpges-1 inhibitors (Kv 11.1) that decrease the rapidly activating delayed rectifier current (

• Given the emerging role of

  2018-11-02

  

  Given the (1) emerging role of IL-3 in early primitive as well as definitive hematopoietic specification (Donahue et al., 1988; Robin et al., 2006; Yang et al., 1986), (2) the fundamental importance of G-CSF and M-CSF in terminal granulocyte and monocyte/macrophage differentiation (Clark and Kamen,

• The reprogramming of somatic cells was

  2018-11-02

  

  The reprogramming of somatic catalase inhibitor was originally demonstrated by producing cloned frogs using somatic cell nuclear transfer (SCNT) into Xenopus oocytes (Gurdon et al., 1958). Reprogramming of mammalian somatic cells has also been achieved using SCNT into oocytes, including those of mi

• We generated immortalized BMSC clones

  2018-11-02

  

  We generated immortalized BMSC clones to perform detailed analysis of functional diversity in BMSC subtypes to levels not previously described. Similar immortalization techniques (e.g., hTERT combined with human papillomavirus E6/E7) have been used for the clonal analysis of BMSCs, which found OAC,

• In summary our findings indicated

  2018-11-02

  

  In summary, our findings indicated that miR-375 promoted the osteogenic differentiation of hASCs both in vitro and in vivo, and miR-375 targeted DEPTOR to inhibit the activity of AKT signaling during this process. Furthermore, YAP1 together with miR-375 established a negative feedback loop to regula

• The stationary solution of the system

  2018-11-02

  

  The stationary solution of the system of equations (1) has the form: where Since the intermode interval Δ0 = 0.05, for calculation convenience, similarly to the supposition made in [6], let us assume that the axial mode of the resonator corresponding to the maximum gain at the 1064.15 nm wavelen

• IOX-2 The present study has considered the

  2018-11-02

  

  The present study has considered the generation of the third harmonic. The ratio of the voltage amplitude at the frequency 3ω to the amplitude of the voltage applied to the sample, i.e., the third harmonic coefficient γ3ω[14], was used as the quantity characterizing the generation intensity. The fie

• and limiting the field variations

  2018-11-02

  

  and limiting the field variations, in the region of oscillations. If the angle θ is equal to the Brewster\'s angle , the two curves coincide. When vertically polarized waves fall on the surface of an ideal dielectric (, is real) at this angle, the reflection coefficient  → 0, and its phase is e

• The systematic devaluation of women is further

  2018-11-02

  

  The systematic devaluation of women is further perpetuated through hegemonic power relations on the maternity ward, leading to the normalization and acceptance of healthcare providers using abusive tactics to gain control and punish disobedience (Jewkes & Penn-Kekana, 2015). Although midwives are th

• Fourth the contextual features we examined appear

  2018-11-02

  

  Fourth, the contextual features we examined appear to have unique and pernicious consequences for women. While differences between states in the personal characteristics of women and men contributed to state variation in mortality to a similar degree, the contextual features explained more than twic

• In a comparative perspective life expectancy is

  2018-11-02

  

  In a comparative perspective, life expectancy is high in Sweden, meaning that even a mother who gives birth at the very advanced age of 50 would be overwhelmingly likely to still be alive when her child is aged 19. Over 80% of women born in Sweden in the 1940 cohort were still alive by age 70 (Stati

• The notion that pets can facilitate social capital goes

  2018-11-02

  

  The notion that pets can facilitate social capital goes beyond the more commonly investigated role of pets as a social icebreaker between strangers, or as a catalyst for social interaction (Hunt, Hart, & Gomulkiewicz, 1992; McNicholas & Collis, 2000; Messent, 1983; Newby, 1997; Robins, Sanders, & Ca

• This issue of contains an article by Yeh

  2018-11-01

  

  This issue of contains an article by Yeh and Schenck about behavioral dyscontrol during sleep emerging with sporadic (non-familial) nocturnal frontal lobe epilepsy (NFLE) . A series of eight cases was reported, with video-polysomnography (vPSG) and sleep EEG documentation, and successful treatment

• Standard methods and procedures for the quality

  2018-11-01

  

  Standard methods and procedures for the quality assessment of alcoholic beverages are based on gas and liquid chromatography, often coupled with mass spectrometry for the structural identification of the individual components [7]. For the enrichment of the aroma substances, several methods have been

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