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Despite the clear evidence of these interventions coverage i
2018-10-30
Despite the clear evidence of these interventions, coverage is still low and therefore their impact to reduce mortality among newborns and children is very poor. The recent Lancet every newborn series (Bhutta et al., 2013, 2014) has clearly highlighted that approximately three-quarters of deaths und
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As stroke related functional measures mRS and BI
2018-10-30
As stroke-related functional measures, mRS and BI similarly deteriorated in both groups (Fig. 4A,B), with no apparent difference. Also, given the studies suggesting favorable effects of statin on cognitive function, whether change of CDR and MMSE score differs between the two groups was of interest.
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We hypothesized that elderly have an augmented
2018-10-30
We hypothesized that elderly have an augmented inflammatory response associated with an impaired immune response leading to immune paralysis after a severe burn. We could not confirm our hypothesis, but we found that during the early phases after burn elderly were hypo-inflammatory with significantl
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We identified an acquired ceritinib resistance mechanism cau
2018-10-30
We identified an acquired ceritinib-resistance mechanism caused by P-gp overexpression in an ALK-rearranged NSCLC patient who was receiving ceritinib therapy. We also demonstrated that ceritinib is a P-gp substrate and that P-gp inhibition reversed ceritinib and crizotinib resistance. While our manu
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br Subjects and Methods br Results br Discussion HnRNP A
2018-10-30
Subjects and Methods Results Discussion HnRNP A1 has been reported as an important autoantigen of the autoimmune response in rheumatic diseases in many articles. Autoantibodies to hnRNP complex have been detected in patients with RA, SLE and mixed connective tissue disease in succession (so
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The link to dietary protein quality is
2018-10-30
The link to dietary protein quality is of particular interest from a public health lens; as the authors note, “dietary intake of essential order Paclitaxel may be insufficient in children with stunting”. Previous research supports this hypothesis: An analysis of dietary and anthropometric data colle
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Although low baseline virus load
2018-10-29
Although low baseline virus load is considered one of the predictive factors for SVR12, many other host, virus and drug related factors are also important and can sometimes affect the virus response to treatment regardless of baseline virus load. The significant existence of Resistance Associated Su
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The Lothian Birth cohorts of and are studies that
2018-10-29
The Lothian Birth cohorts of 1921 and 1936 are studies that were initiated in 1999 and 2004 respectively, originally aimed at uncovering the genetic determinants of cognitive aging. These are follow up studies to the Scottish mental survey that tested the intelligence of almost all children aged 11
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The linkage map underpinning the B
2018-10-29
The linkage map underpinning the B. napus pseudomolecule arrangement was based on a mapping population of only 37 genotyped lines. This limited the resolution of the resource as the 21, 323 mapped markers defined only 527 recombination bins [7]. By increasing the size of the genotyped population to
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Funding from the German Federal Ministry of Education
2018-10-29
Funding from the German Federal Ministry of Education and Research (BMBF) supported parts of this study (Funding code FKZ 16I1619). The Leibniz Center for Agricultural Landscape Research (ZALF) is institutionally funded by the Federal Ministry of Food and Agriculture (BMEL) and the Ministry for Scie
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br Experimental design materials and methods The
2018-10-29
Experimental design, materials and methods The original map was obtained as a TIFF image from [1] and was imported to GlobalMapper v11.01 (Global Mapper Software LLC). The image was then combined with a basemap of South America and the limits of each province and subprovince were set and adjusted
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Earlier mentioned protocols were followed
2018-10-29
Earlier mentioned protocols [1,2] were followed right from the extraction up to qualitative and quantitative analysis of diatoms. Diatoms were identified on the basis descriptions available in the literature [3]. Distribution patterns of diatoms have been displayed in Table 4. Photomicrographs of so
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At the cellular level DCDC is involved in
2018-10-29
At the cellular level DCDC2 is involved in processes such as cellular defense response, dendrite morphogenesis, intracellular signal transduction, regulation of smoothened signaling pathway, regulation of Wnt signaling pathway, and regulation of cilium assembly. At the systems level, DCDC2 is correl
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To date only a few studies
2018-10-29
To date, only a few studies have evaluated SES-related disparities in neural mechanisms of selective attention in children. All these studies revealed neurophysiological differences in children from lower compared to higher SES backgrounds (D’Angiulli et al., 2008; Kishiyama et al., 2009; Stevens et
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Scipioni et al and Chiapasco et al recommended
2018-10-29
Scipioni et al. [21] and Chiapasco et al. [34] recommended that the periosteum should not be stripped off the labial plate in order not to affect the blood supply and to allow rapid revascularization of the expanded plate of bone. The periosteum has another function in treating the mal-fractures tha
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