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Clearly there are limitations to the current
2019-04-23
Clearly there are limitations to the current study. These include the single centre, retrospective nature of the study as well as its relatively small sample size compared with the randomised data. However, the duration of follow up is considerably longer than these trials (Table 1). In conclusion,
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br Materials and methods br Results br Discussion br
2019-04-23
Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential ligand gated ion channel (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation
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OS is Executive Director of
2019-04-23
OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun
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Independientemente del estado de nimo de los agentes del
2019-04-23
Independientemente del estado de ánimo de los agentes del gobierno colonial, ante el fin de la ocupación militar, La Lucha presentaba el advenimiento de la República de Cuba como un hecho con claroscuros para diferentes sectores de la sociedad cubana; por un lado, se anhelaba la salida del gobierno
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Introduction Myelodysplastic Syndrome MDS is a heterogeneous
2019-04-23
Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal
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The studies from several laboratories suggest that
2019-04-23
The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi
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br Methods br Results br Discussion
2019-04-23
Methods Results Discussion For the first time, we report the characteristics of meridian acupoint temperatures in healthy medical college students, from which we can construct a meridian acupoint temperature map. The map vividly shows that the acupoint temperature is consistent within a nar
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CaMKII phosphorylation of L type Ca channels
2019-04-22
CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 purchase CMX001 and predisposing to early afterdepolarizations. Recently identified p
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The ability of tumors to progress to more malignant
2019-04-22
The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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Upon diagnosis the patient s lymphoma and
2019-04-22
Upon diagnosis, the patient׳s lymphoma and HLH represented a therapeutic dilemma. Effective early therapy reduces mortality of HLH from 95% to 30–35% [4]. The HLH-2004 treatment protocol consists of T-cell targeted immunosupression with dexamethasone and cyclosporine, macrophage targeted etoposide w
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However Ethiopia is addressing this situation head on
2019-04-22
However, Ethiopia is addressing this situation head-on. To increase access to oxygen and pulse oximetry, the Ethiopian Ministry of Health (MOH) has responded by undertaking a comprehensive strategic planning process captured as a roadmap for oxygen and pulse oximetry scale-up. A national technical w
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En este art culo se observar n ciertos puntos
2019-04-20
En este artículo se observarán ciertos puntos de los capítulos IX y X de Paradiso, donde el autor claramente se rehúsa Blebbistatin definir a sus personajes y sus discursos, para plantear interrogantes y momentos paradigmáticos de esta imposibilidad clasificatoria que era el objetivo (o utopía) de l
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The circadian variation of VF shows a similar nocturnal patt
2019-04-20
The circadian variation of VF shows a similar nocturnal pattern in patients with BS and ERS [32] (Fig. 2). This is in contrast to the circadian pattern of VTAs in patients with ischemic heart diseases [33]. In a Korean cohort of patients with ERS and BS who underwent implantable cardioverter defibri
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Our results are consistent with previous
2019-04-20
Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].
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cyclic gmp During a mean of months of follow up freedom
2019-04-20
During a mean of 41±29 months of follow-up, freedom from VT or VF was observed more frequently in the non-inducible group (24 of 30 (75%)) than in the inducible group (9 of 21 (43%), P=0.03). The estimated cumulative freedom from VT or VF was 88%, 83%, 75%, and 55% at the 1-, 2-, 3-, and 5-year foll
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