• Several possible nuclear functions for

  2020-08-04

  

  Several possible nuclear functions for EphB4 may be implied from studies of other RTKs that translocate to the nucleus. In prostate cancer, nuclear ERBB3 has been shown to discriminate normal from malignant tissues and between tumours from hormone-sensitive versus hormone-refractory prostate cancer

• Chemical cytometry utilizes sensitive analytical techniques

  2020-08-04

  

  Chemical cytometry utilizes sensitive analytical techniques such as microelectrophoresis or mass spectrometry to analyze and characterize the contents of single GSK-2118436 (Dovichi, 2010; Dovichi & Hu, 2003). Microelectrophoretic chemical cytometry is well-suited to address many of the challenges

• To our knowledge this is the first

  2020-08-04

  

  To our knowledge, this is the first report of an oncocytoma expressing alpha-enolase or causing autoimmune retinopathy and optic neuropathy. Although generally considered benign, oncocytomas have rarely been associated with paraneoplastic syndromes, including tumor-induced hypertension, erythrocytos

• Sexually dimorphic testosterone hydroxylase activities have

  2020-08-04

  

  Sexually dimorphic testosterone hydroxylase activities have been suggested as a biomarker of endocrine disruption caused by xenobiotics (Wilson et al., 1999). The results from the studies reported here suggest that dietary exposure to the endocrine active test compounds, all of which have demonstrat

• br Acknowledgments This work was supported

  2020-08-04

  

  Acknowledgments This work was supported in part by Grants from the Ministry of Education, Culture, Sports, Science and Technology of Japan (22370047, 23116505, 25116704, 25860042, and 26291017); the Japan Science and Technology Agency (AS221Z00794F, AS231Z00139G, and AS251Z01788Q); the Naito Foun

• br Materials and Methods br

  2020-08-03

  

  Materials and Methods Acknowledgements Introduction Collagen fibrillogenesis, the assembly of collagen fibers, is a critical process in the development, maturation, and repair of mammalian tissue. Alterations in the structure and amount of deposited collagen fibers can greatly alter the int

• The results of our study demonstrated that

  2020-08-03

  

  The results of our study demonstrated that HSL activation by kinsenoside-mediated PKA activation was coordinated with perilipin phosphorylation and facilitated efficient lipolysis, resulting in increased glycerol release and decreased lipid accumulation. The localization and interplay of perilipin a

• br Materials and methods br Results br

  2020-08-03

  

  Materials and methods Results Discussion Systemic responses to HH are multifaceted, and they function to restore homeostasis to allow survival and p97 under normal conditions. However, excessive and frequent HH stress results in deleterious health consequences, such as impaired cerebral au

• br Materials and methods br Results

  2020-08-03

  

  Materials and methods Results Discussion Cardiac hypertrophy is characterized by an increased cardiomyocyte size, excess protein synthesis, and thickened ventricular walls. Although myocardiac hypertrophy initially might be adaptive and compensatory, a sustained pathological hypertrophic re

• With the AR gene previous research has found associations of

  2020-08-03

  

  With the AR gene, previous research has found associations of the short Etomoxir sale of both the CAG and GGC repeat polymorphisms with behavioural characteristics typical of high P. In the present study, the short CAG genotype was significantly associated with high P in males only. In females, the

• Environmental cues such as microbial

  2020-08-03

  

  Environmental cues, such as microbial, dietary, and neuronal signals, regulate the differentiation and function of ILC3s. However, the identities of any additional cues and the receptors that detect them remain unknown. An important class of proteins enabling cells to sense extracellular cues are G-

• gssg synthesis NHEJ does not require sequence homology betwe

  2020-08-03

  

  NHEJ does not require sequence homology between the DNA ends as a prerequisite for ligation. As a result, this process can be error prone while HR is generally considered to be an error-free process. However, how a cell chooses whether to repair a DSB through NHEJ or HR, and how DNA-PK is activated

• br Experimental br Acknowledgements This research was financ

  2020-08-03

  

  Experimental Acknowledgements This research was financially supported by the Scientific and Technological Developing Scheme of Jilin Province of People\'s Republic of China (20150101225JC). Introduction Obesity is a serious health risk signal characterized by excess accumulation of triglyc

• In the meta analysis apart from Kano s study

  2020-08-01

  

  In the meta-analysis, apart from Kano\'s study (Kano et al., 2012), we found that the significant associations of previous studies were marginal and changed along with the genetic effect models (Porcelli et al., 2015; Terock et al., 2018). Given the inconsistency in genetic effect models and the het

• br Acknowledgements br Introduction Acute lung

  2020-07-31

  

  Acknowledgements Introduction Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), a more severe form of ALI, are devastating clinical syndromes characterised by alveolar-capillary membrane hyper-permeability, oedema, infiltration of neutrophils into interstitial spaces, neu

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